Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq - ScienceDirect
Perturb-Seq是研究某种现象的有力工具 – 子夜星河
Targeted Perturb-seq enables genome-scale genetic screens in single cells | Nature Methods
Approaches to maximize sgRNA-barcode coupling in Perturb-seq screens | bioRxiv
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response - ScienceDirect
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion | Nature Genetics
Direct capture Perturb-seq – CRISPR meets single-cell RNA sequencing to offer unprecedented detail and depth of insight from such genetic disruption studies | RNA-Seq Blog
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes | Science
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response - ScienceDirect
In vivo Perturb-seq: scaled investigation of gene functions in the brain - YouTube
CRISP-Seq Barcoded sgRNA Libraries (Perturb-Seq, CROP-Seq) - Cellecta
Vector structure of single-cell perturbation assays. The sgRNA barcode... | Download Scientific Diagram
Researchers apply the Perturb-Seq method to a living organism for the first time | RNA-Seq Blog
Design and validation of direct-capture Perturb-seq for 3′ and 5′... | Download Scientific Diagram
A robust strategy combining CRISPR screening with RNA-sequencing... | Download Scientific Diagram
Perturb-seq: K562 - Single Cell Portal
Single-Cell CRISPR Screening Service: Perturb-Seq, CRISP-Seq, CROP-Seq - Cellecta
Figure 4 from Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens | Semantic Scholar
Introducing the Next-Generation of Genetic Screening
Researchers use CRISPR technology to create map tying every human gene to its function | Whitehead Institute
Genome-Wide Perturb-Seq
Direct capture of CRISPR guides enables scalable, multiplexed, and multi-omic Perturb-seq | bioRxiv
Perturb-seq – Enables Large-Scale Analysis of Complex Genetic Interactions Using CRISPR-Based Gene Perturbation and Single-Cell RNA Sequencing | RNA- Seq Blog
In vivo Perturb-Seq | Xin Jin
Joseph Replogle on Twitter: "4. But Perturb-seq allows for more than clustering. scRNA-seq phenotypes allow us to study the phenotypic consequences of genetic perturbations, transcriptional programs, and “composite phenotypes” like RNA processing,
